This paper suggests a possible proximity between Jacobi and Deleuze on the topic of individuality. I argue that three related points could bring Deleuze and Jacobi together. Firstly, both agree about the significant role of individuality in the sense that their philosophies would not be consistently sustained without this element. Secondly, both critically move in an epistemological direction opposed to the epistemological direction of the philosophies of identity. Thirdly, both could not be perfectly understood apart from the influence of the philosophies of Spinoza, Leibniz, Hume, and German idealism.The plane of this possible proximity between Jacobi and Deleuze goes like this: I will examine the main element of their philosophies—the priority of individuality—in light of their engagement with Spinoza, Hume, and Kant.